Binge drinking could show different brain effects depending on gender
Males and Females affected differently by binge drinking - short science articles and news

In an animal model of binge drinking, researchers have been able to show that in brain regions associated with addiction, gene expression is affected differently in male and female mice. The brain region in question is called the nucleus accumbens, which is considered the addiction center of the brain. Scientists were able to show that in females the genes associated with hormonal signaling and immune function are affected, while in male mice the nerve signaling was affected. Further, they were able to show that pharmacologically manipulating a brain circuit only affected binge drinking in male mice with no effect on the female mice indicating a dichotomy in the effects of alcohol based on gender.

Read the full story: Genetic and Bioengineering news
Scientific publication: Frontiers in Genetics