Researcher Dena Dubal, from the UCSF Weill Institute of neurosciences, wants to reverse ageing and ameliorate dementia. The protein, Klotho, first discovered by Japanese researchers and found to increase longevity in mice might just be the answer. Dr Dubal found that higher amount of klotho resulted in better cognitive functioning. The next step is to find out how does it work without crossing the blood-brain barrier. This is exciting since maybe some day klotho becomes a therapy for humans to protect the brain against ageing.
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