New technology allows obtaining PET images of the brain in freely moving animals
Brain scans in moving animals now possible - daily short science news

PET (positron-emission tomography) scans have long been used in research for imaging the brain of small animals. However, the classical approach requires the animals to be anesthetized, which perturbs many neurological parameters. But now, researchers report achieving PET scans in awake, moving animals.

The technique allows for simultaneous brain imaging and behavioral tests which has great potential for research. To achieve this, scientists built a system containing a motion-sensitive observation chamber which adapts to the animal’s head position within the PET field-of-view.

The new system was successfully tested in an experiment measuring the rate of binding of specific compounds to dopamine receptors in the brain. Thus, this approach holds important applications in neuroscience research.

Read the full story: Physics World
Scientific publication: Neuroimage