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Brain regions show hyper-connectivity in Cannabis abusers

Dr. Nora Volkow of the National Institute on Alcohol Abuse and Alcoholism and her colleagues as a part of the Human Connectome Project have shown that chronic cannabis abuse results in higher resting state connectivity especially in the dopaminergic circuit of the brain which is implicated in the goal seeking behavior, reward and habit formation. This state of hyper-connectivity was also more pronounced in those individuals who began cannabis use in early adolescence. The researchers speculate that this might be the source of heightened emotional disturbances and higher risk of psychosis amongst these individuals.

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