Diabetes and its link to Alzheimer's revealed
Alzheimer’s linked to insulin signaling failure - interesting science news

Researchers have found that impaired insulin signalling in the brain diminishes its learning and memory properties as a result of which those with type 2 diabetes are at a greater risk of developing Alzheimer’s disease.

Researchers developed a new mouse model in which they blocked the expression of insulin and insulin like growth factor receptors in the brain regions involved with learning and memory by testing these mice in a maze.

These mice also had decreased expression of the glutamate receptor GluA1 which is involved in making important brain connections. This could be the reason for altered mood and cognition impairment in these mice.

Read the full story: Joslin Diabetes Center
Scientific publication: PNAS


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