Epilepsy is a disease caused by instability of brain activity
A thermostat in the brain to balance electrical activity: implication for future epilepsy treatment - brain short science news

Researchers have discovered how the setpoint of neuronal activity is determined, a thermostat which prevents the brain from going into a state of epilepsy (too much brain activity) or coma (too little brain activity).

The setpoint is maintained by calcium in the brain cell’s mitochondria, the powerplants of the cells. Interestingly, a drug commonly used to treat multiple sclerosis, interferes with this mitochondrial thermostat, and may one day, once chemically optimized, be used to treat epilepsy.

This is good news for patients with the Dravet syndrome, a dangerous childhood form of epilepsy for which there is no treatment at present.

Read the full story: Tel Aviv University
Scientific publication: Neuron