DNA that does not code for proteins is important for brain development
Non-coding DNA essential for normal brain development

The mystery of what highly conserved, but not protein-encoding, DNA is for has finally been solved: it regulates the expression of genes that do code for proteins, and by doing so guides brain development. When researchers removed this non-coding DNA in experimental mice, they observed abnormalities in the hippocampus that resemble those found in Alzheimer’s disease or could facilitate epilepsy and dementia. Future studies will have to reveal whether patients with these disorders have mutations in these important but understudied DNA sequences.

Read the full story: www.nature.com/articles/
Scientific publication: www.cell.com/cell/