New approach to treat cancers, including certain types of lung cancer
Targeting a cancer cell’s metabolic need to fight tumors - health science news

Researchers have successfully targeted an understudied metabolic pathway in cancer cells to arrest cell growth and survival. This pathway concerns oxidative phosphorylation, which can now be inhibited by a newly developed drug. The drug was tested in preclinical studies for treating lung cancers with a special genetic mutation, which makes the cancerous cells sensitive to the drug, as these cells consume more oxygen and display increased oxidative phosphorylation for their metabolic needs. This study therefore provides the basis of the development of new medication for a number of cancers.

Read the full story: University of Texas – MD Anderson Cancer Center
Scientific publication: Nature Medicine – drug
Scientific publication: Nature Medicine – preclinical lung cancer study