The elderly suffer more serious complications from infections and benefit less from vaccination than the general population
T cell function in the elderly weakens through defective metabolic pathway - health short science news
A metabolic pathway in the immune system’s T cells that makes proteins and DNA is less active in T cells from aged mice.

This pathway plays a central role in cell replication and thus building the army of immune cells that attack invaders. When researchers added products (formate and glycine) of the metabolic pathway to weakened T cells, these cells became fully functional again, proliferated well and did not die prematurely.

These results indicate that it should be possible to boost the immune system of elderly people to protect them better against the consequences of infections.

Read the full story: Harvard Medical School
Scientific publication: Proceedings of the National Academy of Sciences of the USA