Cancer cells have special metabolic demands that are now being explored for new treatment options
Starvation of cancer cells to arrest their growth

Researchers from Vanderbilt University Medical Center have tapped into the unique metabolic demands of cancer cells to deprive these cells from glutamine, an amino acid necessary for biosynthesis, cell communication and protection against oxidative stress. They developed a small molecule that effectively blocks the glutamine transporter that is expressed on cancer cells for glutamine uptake. The molecule inhibited cell growth and proliferation and increased cell death in the laboratory, and might thus be at the basis of news ways to treat cancers.

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