Migration of primordial germ cells in the human embryo. Image: Laurence Zulianello
Origin of some cancers in young women revealed . health science news

A new study has found that primordial germ cells (cells that will give rise to oocytes during adulthood) at times do not migrate to the gonads, but end up in the pancreas or the ovaries during embryonic development. Here, they increase the risk for cancer, which can occur thirty years later. This mechanism underlying these so-called « mucinous cancers » was found following large-scale analyses of genomic data. The faulty migration of primordial germ cells explains why only young women, not men, can have pancreatic cancer without the involvement of sex hormones.

Read the full story: Université de Genève
Scientific publication: Journal of Pathology