Individual cancer cells are imaged to determine whether drugs have reached them. Image: Erik Sahai, Francis Crick Institute
New technique to assess whether cancer medication reaches the tumor - health science news

Scientists have developed a new technique that allows them to determine whether the drugs they use to treat a cancer actually reach the tumor. The technique makes use of the interaction between two light-sensitive molecules, one labelling the DNA, and the other, the drug doxorubicin, that starts to emit light once it is close to the DNA. The results in mouse ovary cancer show that there is a lot of variability between the number of cells reached within the same tumor and between tumors. This is important to know, as failure of chemotherapy to reach all cancer cells might reduce positive treatment outcomes, and would indicate that other routes of drug delivery should be chosen, or that other drugs should be used to treat the cancer.

Read the full story: The Francis Crick Institute
Scientific publication: Nature Communications