Viruses (AAV) are injected directly into the vitreous of the eye (top) to deliver a gene coding for a light-sensitive receptor, which will be epxressed in ganglion cells to make them sensitive to light. Image: John Flannery, UC Berkeley
Making blind mice see again with a single gene injection - health short science news

Researchers have developed a relatively simple method that restored vision in blind mice suffering from retinal degeneration. The mice were able to see motion, brightness changes over a thousandfold range and detail on an iPad that was sufficient to distinguish letters.

The technique consists of injection an inactivated virus that carries a gene for a light-sensitive receptor, the green cone opsin. This is targeted to the retinal ganglion cells, and makes them light-senstive.

The researchers expect to start clinical trials on humans with retinal degeneration in as little as three years.

Read the full story: University of California – Berkely
Scientific publication: Nature Communications