Human gut microbes metabolize over 150 therapeutic drugs, highlighting the role bacteria play in determining how well individuals respond to medications
Intestinal bacteria influence the effect of commonly used medicines  - health short science news

Commonly used drugs such as cancer medication, antidepressants, birth-control contraceptive pills, and those that lower blood pressure or cholesterol are converted by bacteria in the intestines in such a way that the effect in our body may change as a result. The difference in gut bacteria population between individuals may explain why the effect of medicines can differ from patient to patient.

American scientists exposed 271 types of pills in culture dishes to 76 different common human gut bacteria and saw a change occur in two thirds of the drugs: the chemical composition of the drugs changed under the influence of at least one bacterial strain.

This discovery may have consequences for the treatment of various diseases, and promote personalized medicine.

Read the full story: Yale University
Scientific publication: Nature