Blocking signals from a small number of neurons in the brain produces bone growth in female mice. Image: Holly Ingraham/UC San Francisco
Discovery of a new mechanism to grow strong bones for future treatment of osteoporosis - health short science news

Scientists have found that blocking just a few neurons in the brain, in the hypothalamic arcuate nucleus to be precise, of female mice boosts bone growth enormously. Bone mass can increase to 800% and the bones remain strong until old age.

Importantly, blocking these brain cells in female mice that were already suffering from osteoporosis restored bone loss, suggesting these cells control bone formation.

How the brain cells involved do this is not clear as yet, indicating that the scientists have discovered a new mechanism of how bone growth is controlled, and thus holds great promise for new treatment options.

Read the full story: UCLA
Scientific publication: Nature Communications


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