Oxidative stress activates neurons that promote sleep
Brain process involved in aging also promotes sleep - health short science news

Oxidative stress, a condition in which cells cannot cope properly with reactive oxygen species, is known to be a cause of biological aging. Now, scientists have found that oxidative stress is also at the basis of sleep, at least in fruit flies.

Sleeplessness causes oxidative stress, and this drives a chemical conversion of a small molecule, NADPH. NADPH then opens a channel, so that electrical current can pass into the neurons that promote sleep to activate them.

Researchers say that this newly discovered mechanism could lead to the development of a new generation of sleeping pills.

Read the full story: University of Oxford
Scientific publication: Nature