Bacterial persister cells manipulate our immune system from the inside
Bacteria persister cells escape from antibiotics and weaken the immune system - health short science news

During an infection, some bacteria go into an inactive “stand-by” mode, and are then swallowed by macrophages, cells of our immune system. Now, researchers have found that these bacterial “persister” cells are not inactive after all, but actually change the macrophages from an inflammatory to a non-inflammatory cell.

This weakens the defense against the bacteria when they spring back to life, and against new invading bacteria.

This mechanism explains why sometimes infections reappear after antibiotics treatment, from which the persister cells escape by hiding in the cells that should kill them.

Read the full story: Imperial College London
Scientific publication: Science


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