NLRP12 promotes growth of good bacteria that help to protect against obesity
An anti-inflammatory protein protects against obesity through microbiota - health short science news

Scientists have found that the anti-inflammatory protein NLRP12 protects mice against obesity when they are fed a high-fat diet. It does so by promoting the growth of healthy gut bacteria, known as Lachnospiraceae. These bacteria produce the small molecules butyrate and propionate, which improve gut health and protect against obesity and insulin resistance. Interestingly, in obese people, the expression of NLRP12 tends to be lower, suggesting that the results found in mice are relevant to humans. NLRP12 might thus be a novel target for the treatment of obesity.

Read the full story: University of North Carolina at Chapel Hill
Scientific publication: Cell Host & Microbe