Study discovers mechanisms involved in development of lung cancer

Aug 19, 2018 Alexandru Ciobanu


Chromosome 15q25.1 has been known as a genetic component responsible for increasing the susceptibility to lung cancer. Now, a new study discovered two main cellular pathways, involving the chromosome, that can modify t... Read more

Disrupted nitrogen metabolism plays a role in cancer

Aug 13, 2018 Erwin van den Burg


Nitrogen is a building block of proteins, RNA and DNA, and is therefore in high demand by cancer cells. Scientists have now found that disrupted nitrogen metabolism in the liver reduces the concentration of a nitrogeno... Read more

Rotavirus vaccine reduces death in infants by a third in Malawi

Aug 13, 2018 Alexandru Ciobanu


Rotavirus remains a leading cause of severe diarrhea and death among infants in many countries from Africa and Asia. To combat the situation, many regions have added the rotavirus vaccine to their routine immunization ... Read more

Making cancer treatment less toxic with the help of machine learning

Aug 12, 2018 Alexandru Ciobanu


Cancer patients must often endure a combination of radiation therapy and multiple drugs taken every month, which leads to a variety of adverse effects. In a quest to minimize the toxic effects of cancer drugs, a team o... Read more

Glaucoma may be an autoimmune disease

Aug 10, 2018 Erwin van den Burg


Surprising new scientific findings suggest that glaucoma, which is characterized by retina damage and can lead to blindness, is an autoimmune disease. Experiments in mice showed that retina cells are destroyed by the b... Read more

Early life onset of diabetes type 1 shortens life by 18 years for women

Aug 10, 2018 Erwin van den Burg


New research has shown that the age at which diabetes type 1 manifests itself is an important predictor of life expectancy. More specifically, development of diabetes type 1 before 10 years of age results in a loss of ... Read more

Bacteria becoming resistant to hospital hand disinfectant

Aug 03, 2018 Alexandru Ciobanu


A key component of current disinfectant hand rubs is alcohol, which is pretty effective in killing bacteria. However, new research shows that a certain type of hospital super-bacteria is becoming increasingly tolerant ... Read more

New drug discovery system identifies drugs for undruggable enzymes in disease

Jul 27, 2018 Erwin van den Burg


Phosphatases are a class of enzymes that often act as a brake on iintracellular signalling, thus switching off certain processes within cells. Until now, it has been extremely difficult to develop drugs that act specifically on one phosphatase only, but now research... Read more

Cell biological mechanism discovered that could protect against Huntington’s disease

Jul 26, 2018 Erwin van den Burg


The protein ubiquitin ligase UBR5 has been found to inhibit the formation of toxic protein aggregates in neurons that cause Huntington’s disease. These aggregates are formed as a consequence of mutations in the h... Read more

Blood test helps to decide which prostate cancer therapy to choose

Jul 25, 2018 Erwin van den Burg


A new blood test has been developed that will help oncologists to decide whether a hormonal or a chemotherapy should be followed for the treatment of advanced prostate cancer. The test is based on the presence or absen... Read more

Surprising virus population changes in inflammatory bowel disease

Jul 25, 2018 Erwin van den Burg


The bacteriophage population in the intestines, the collection of viruses in the guts that infect and often kill bacteria, is varied in healthy persons, reflecting the rich variety in intestinal bacteria. Now researche... Read more

Women under-treated for heart attack have higher risk of dying then men

Jul 23, 2018 Alexandru Ciobanu


An Australian study reveals that women admitted to hospitals with serious heart attacks are half as likely as men to get proper treatment. Moreover, six months after hospital discharge, death rates, and serious adverse... Read more

Reversing skin wrinkling and hair loss associated with aging

Jul 22, 2018 Erwin van den Burg

Scientists have for the first time managed to reverse skin wrinkling and hair loss during aging. In a mouse model, they found that restoring the function of mitochondria by switching off an enzyme that is responsible f... Read more

Is Parkinson’s disease an autoimmune disorder?

Jul 20, 2018 Erwin van den Burg


New research has found that a certain class of T immune cells can kill dopamine-producing cells in the midbrain, exactly the same neurons that die in Parkinson’s disease. T cells are especially abundant in the mi... Read more

New molecular DNA shield discovered with major implications for cancer treatment

Jul 19, 2018 Erwin van den Burg


Why do some breast cancer patients not respond to PARP-inhibitors or platinum-based chemotherapy? The answer lies in the newly discovered protein complex, called “Shieldin”, that shields damaged DNA, so tha... Read more

Risk for autism influenced by the mother’s microbiome

Jul 18, 2018 Erwin van den Burg


A new study shows that the microbiome of the mother during pregnancy determines the risk for autism and other neurodevelopmental disorders in the child. It appears that the mother’s microbiome is extremely import... Read more

Pollen carry bacteria that cause respiratory problems

Jul 18, 2018 Erwin van den Burg


Pollen of the very common plant Artemisia vulgaris (mugwort in english) can cause hay fever, but when they carry bacteria, especially Pseudomonas luteola, they get even more aggressive, a new study reports. The endotox... Read more

Anti-cancer effects of omega-3 fatty acid metabolite

Jul 16, 2018 Erwin van den Burg


You don’t get high, but cancers get down from endocannabinoids that are produced when the body metabolizes omega-3 fatty acids, a new study in mice showed. Being related to cannabinoids found in marijuana, these ... Read more

New technique to assess whether cancer medication reaches the tumor

Jul 13, 2018 Erwin van den Burg


Scientists have developed a new technique that allows them to determine whether the drugs they use to treat a cancer actually reach the tumor. The technique makes use of the interaction between two light-sensitive mole... Read more

Worrying about your food’s food

Jul 11, 2018 Erwin van den Burg


Salmon, even those that are farmed under environmentally clean conditions, can be contaminated with so-called persistant organic pollutants, a new study reports. This is because their feed can be sourced from regions w... Read more