Brain region for loss of pleasure identified
Where does loss of pleasure in depression arise in the brain? - short science news and articles

Researchers have found out the brain region associated with the loss of pleasure seen in depression.

Using experiments conducted in marmosets, which are non-human primates, they identified the brain region ‘area 25’, which is a part of the frontal cortex. Excessive excitement of the area 25 leads to blunting of the excitement usually associated with a reward pointing towards its role in anhedonia (i.e. loss of pleasure).

Using PET scan imaging, researchers observed that increased activation of ‘area 25’ had a trickle down effect on other brain regions which also become more active, which indicates that it is a part of a larger circuitry involved in feeling pleasure.

Read the full story: Neurosciencenews
Scientific publication: Neuron


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