News about cancer: cancer cells can hide from the immune system so that immunotherapy stops working
Why immunotherapy rarely stops cancer - cancer short science news

Scientists have found out why immunotherapy to fight a cancer initially shrinks a tumor, but cannot turn this into long-term silencing or destruction of cancer cells. Cancer cells can apparently hide themselves from the immune cells (known as T cells) that stimulated by immunotherapy to kill them. Cancer cells can stop displaying molecules on their membranes that T cells need to recognize and then attack them. Fortunately, the researchers found that two already existing medications for the treatment of some cancers, could stop the cancer cells from ceasing the expression of the marker molecules. Thus, this study explains why immunotherapies do not have a long lasting effect, and indicates how immunotherapies might be improved for more effective treatment.

Read the full story: Fred Hutch Cancer Research Center
Scientific publication: Nature Communications